MRC1 and colorectal carcinoma: As shown in Figure 7, the FBLN2 (aa330–349)/T antigen, CSF1 (aa370–395)/(T + di-ST), MRC1 (aa1083–1101 and aa1215–1229)/T antigen, FGA (aa354–367, aa511–527 and aa559–573)/ST or Sialyl Core 1, and C7 (aa692–701)/di-ST achieved an AUC value of >0.90, demonstrating that these O-glycoforms have high sensitivity and specificity for advanced CRC diagnosis.