GPX3 and cancer: ROC curves were used to verify that GPX3 is a valuable diagnostic biomarker in several types of cancers, including BRCA, COAD, LUAD, stomach adenocarcinoma (STAD), head and neck squamous cell carcinoma (HNSC), kidney renal papillary cell carcinoma (KIRP), and THCA, as shown in Figure 1C (AUCs > 0.7).