ROC curves were used to verify that GPX3 is a valuable diagnostic biomarker in several types of cancers, including BRCA, COAD, LUAD, stomach adenocarcinoma (STAD), head and neck squamous cell carcinoma (HNSC), kidney renal papillary cell carcinoma (KIRP), and THCA, as shown in Figure 1C (AUCs > 0.7). The gene discussed is GPX3; the disease is head and neck squamous cell carcinoma.