GPX3 and metastatic malignant neoplasm in the lymph nodes: Similarly, in STAD, we used univariate analysis to find that higher GPX3 expression (p = 0.008; HR = 1.533), M1 stage (p = 0.014; HR = 2.052), N1-3 stage (p = 0.004; HR = 1.783), lymph node metastasis (p = 0.002; HR = 1.933) were risk factors for OS.