We focused more on those miRNAs that were predicted to bind to ALS-related genes, including TARDBP, SOD1, C9orf72, FUS, SQSTM1 (p62), and UBQLN2. For example, hsa-miR-340-5p (SOD1-ALS exclusively) was combined with UTR of SOD1 potentially as a 7mer-A1 type [an exact match to positions 2–7 of the mature miRNA (the seed) followed by an “A”], while hsa-miR-199a-3p and hsa-miR-30b-5p (two of them were C9orf72-ALS exclusively) were predicted to combine with the UTR of C9orf72 as 7mer-m8 type (an exact match to positions 2–8 of the mature miRNA). This evidence concerns the gene SQSTM1 and amyotrophic lateral sclerosis.