In recent examples that likely exploit this mechanism, conjugate vaccines incorporating the tumour-associated carbohydrate antigens, MUC-1 [155], GM3 [156] or sialyl-TN (STN) [157] successfully induced antigen-specific IgG antibodies that were shown to induce antigen-specific tumour cell death through complement-dependent cytotoxicity. The gene discussed is MUC1; the disease is neoplasm.