To further study the biological functions of AKR1B10 in PBC, 11 samples of PBC in GSE61260 were divided into the AKR1B10 low- (6 samples) and AKR1B10 high-expression (5 samples) groups, according to the median expression levels of AKR1B10. This evidence concerns the gene AKR1B10 and primary biliary cholangitis.