Moreover, the KEGG pathway enrichment analysis found that the main enrichment pathways of BMs differentially expressed genes included ECM-receptor interaction, focal adhesion, protein digestion and absorption, human papillomavirus infection, PI3K-Akt signaling pathway, small cell lung cancer, axon guidance, arrhythmogenic right ventricular cardiomyopathy, hypertrophic cardiomyopathy, and dilated cardiomyopathy (Figure 6B). The gene discussed is AKT1; the disease is human papilloma virus infection.