These include KCNA2, KCNA3, KCNA10, LAMTOR5, PROK1, RBM15, and SLC16A4. Potassium voltage-gated channel gene expression have previously been shown to change in expression in the heart in response to hypothyroidism in rats (Nishiyama et al., 1998). The gene discussed is KCNA3; the disease is hypothyroidism.