SORL1 and Alzheimer disease: Apolipoprotein E (ApoE clusterin (also known as apolipoprotein J), SORL1 (sortilin-related receptor 1), and ABCA7 ((ATPbinding cassette, sub-family A, member 7) are a few of the genes involved in lipid homeostasis that have been linked to AD in genome-wide association studies (GWAS) (Kao et al., 2020).