Elevated expression of tRF3-Ile-AAT-1, tiRNA5-Lys-CTT-1, tiRNA5-Arg-CCT-4, and tRF5-Arg-TCG-3 were measured in the urinary exosomes of LN compared with SLE without LN patients (Figures 4B–J), implying urinary exosomes derived tsRNAs may serve as promising biomarkers for the diagnosis of LN. Here, TBPL2 is linked to lobular neoplasia.