SAMHD1 and ovarian cancer: SAMHD1 expression was re-evaluated by immunohistochemistry in ovarian cancer archival biopsies (Figure 3A), that were classified as SAMHD1 positive or negative depending on the percentage of SAMHD1 stained tumoral cells [positivity was arbitrarily defined as those with cellular positivity ≥25%, based on previous reported thresholds (11)].