Anti-AchR autoantibodies and striational autoantibodies (anti-titin, anti-heart muscle, and anti-skeletal muscle autoantibodies) have been described in both ICI-induced MG and myositis (21, 26–30), while myositis-specific autoantibodies (e.g., anti-Jo-1, anti-Mi-2 or anti-signal recognition particle autoantibodies) are mostly negative (31, 32). Here, TTN is linked to myositis disease.