Recently, ZBP1 has been found to be involved in the occurrence and development of various tumors, including breast cancer (71–74), melanoma (75–77), colorectal cancer (76, 77), non-small cell lung cancer (76), multiple myeloma (78), ovarian cancer (79), urothelial carcinoma (80), fibrosarcoma (71), and kidney renal clear cell carcinoma (81). The gene discussed is ZBP1; the disease is colorectal cancer.