GSEA of differentially expressed genes in RA‐FLS after TNFα stimulation based on RNA‐seq data of GSE129486 dataset revealed the involvement of TNF signaling pathway, NF‐κB signaling pathway, response to TNF, focal adhesion, cell adhesion molecule (CAM) binding, and so on (Figures 2E,F and S2A,B). This evidence concerns the gene NFKB1 and rheumatoid arthritis.