LUAD patients with a high level of SIRT2 expression have a high level of effector memory T cell, resident memory T cell, T cell exhaustion, resting Treg, Th1, monocytes, and DCs infiltrating into the tumor tissue (Figures 6Z, R, AD, and Supplementary Figures 2O, Q). The gene discussed is SIRT2; the disease is Alzheimer disease.