TNNT2 and fibrosis: In contrast to the strong association of hs-cTnT and the presence of replacement fibrosis with LGE, the association of hs-cTnT with interstitial fibrosis (defined as the 4th quartile of CMR-determined ECV) was more modest, with subjects in the 4th quartile of hs-cTnT having a 40% greater odds compared to the lowest quartile (OR = 1.4 [95%CI 1.0-1.9]), an association that was similar after adjustment for demographics and CVD risk factors (OR = 1.7 [95% CI 1.1-2.8]).