Identifying a preclinical phenotype using cardiac magnetic resonance (CMR), amino terminal B-type natriuretic peptide (NT-proBNP) was associated with interstitial (diffuse) fibrosis represented by an increase in extracellular volume (ECV) and high sensitivity cardiac troponin T (hs-cTnT) was associated with the presence and extent of replacement (focal) fibrosis (7, 9). This evidence concerns the gene TNNT2 and fibrosis.