CD4 and coinfection: Recently, several studies in Caucasians and Thailand found that ethnicity, HBV viral load, CD4 cell count, HBeAg, and quantification of HBsAg were significantly associated with HBsAg clearance among patients with HIV/HBV coinfection treated with long-term TDF-containing ART (Zoutendijk et al., 2012; Matthews et al., 2013; Jiang et al., 2019; Audsley et al., 2020; Bremen et al., 2020).