A combination of six biomarkers including Ang-2, CXCL10, sFlt-1, PCT, sTREM-1 and sICAM-1 in 2011 was able to predict mortality in Ugandan children with SM and showed 95.7% sensitivity and 88% specificity in differentiating fata and non-fatal cases (Erdman et al., 2011). Here, CXCL10 is linked to systemic mastocytosis.