PROCR and cutaneous mastocytosis: Recently, the subgrouping of patients with CM revealed that severe thrombocytopenia was associated with increased parasite biomass, while moderate thrombocytopenia was associated with more Group A–EPCR var transcripts (Sahu et al., 2021a), suggesting that these elements could be investigated in combination with thrombocytopenia to determine CM prognosis, although further research is needed.