As a result, seven molecules were identified that can discriminate between individuals with LTBI and active TB, including IL-2 (AUC, 0.91; sensitivity, 0.87; specificity, 0.61), IP-10 (0.86, 0.77, and 0.73), IL-5 (0.85, 0.64, and 0.75), IL-13 (0.85, 0.75, and 0.71), IFN-γ (0.80, 0.67, and 0.75), IL-10 (0.80, 0.68, and 0.74), and TNF-α (0.78, 0.67, and 0.64). The gene discussed is IFNG; the disease is tuberculosis.