The acute phase inflammatory proteins serum amyloid A and CRP are elevated in our post-COVID-19 cohort, in common with post-sepsis patients; but there are no differences in the levels of the leukocytic pyrogen and component of the inflammasome complex, IL-1β, from healthy control patients, in contrast with the findings of another study of patients reporting post-acute sequelae of COVID-19 (23). This evidence concerns the gene CRP and COVID-19.