A multivariate logistic model for the predictors of mortality showed that age of over 65 years, higher CRP or D-dimer or glycaemia greater than 10 mmol/L upon admission, history of HF and CKD, prehospital insulin use, and in-hospital loop diuretics use were associated with a higher death rate, while the in-hospital use of statin, thiazide diuretic, and CCB were associated with lower mortality (Table 2). This evidence concerns the gene INS and chronic kidney disease.