By calculating the expression correlations of 10 CRGs, we found that LIAS, LIPT1, DLD, DLAT, PDHA1, PDHB, MTF1, GLS, and CDKN2A showed a positive correlation with other genes in HCC, while FDX1 negatively correlated with multiple genes. The gene discussed is LIAS; the disease is hepatocellular carcinoma.