HMGCR and colorectal carcinoma: Among the eight targeted genes, HMGCR, LDLR, PCSK9, PLA2G7, and SCARB1 were overexpressed in CRC tumor tissues as compared to normal tissues (Figures 3F–K), while ABCA1, ABCC3, and PGR exhibited low expression levels in CRC tumor tissues (Figures 3D–I).