MAPK8 and persistent truncus arteriosus: The miR-327 expression is investigated to be upregulated in TAC-induced cardiac fibrotic tissue and Ang II-induced cardiac fibroblasts, and the inhibition of miR-327 expression restrains the TAC-induced ERK1/2, p38MAPK, and JNK phosphorylation levels, thereby attenuating the cardiac fibrosis (Ji et al., 2018).