Another study by Halmaciu et al. assessed disease progression and the predictive value of the Inflammation Index (AISI) and total system score (TSS) for invasive mechanical ventilation and mortality in patients with high levels of serum interleukin 6 (IL-6) and COVID-19; they found that high MLR, NLR, SII, SIRI, AISI, IL-6, and TSS values were strong predictors of invasive mechanical ventilation and mortality [20]. Here, IL6 is linked to COVID-19.