A WHO study in low- and middle-income countries found that only 70.6% of patients with cerebrovascular disease and 81.2% of patients with ischemic heart disease (IHD) were prescribed aspirin, while only 37.8% and 39.8% were prescribed angiotensin-converting enzyme (ACE) inhibitors, respectively [19]. The gene discussed is ACE; the disease is coronary artery disorder.