PLOD1 and metabolic syndrome: However, a significant association of serum LH quintile with MetS was observed in postmenopausal women (P for trend= 0.002), and a negative association of fifth quintile of LH with the risk of MetS was observed (OR: 0.629; 95% CI: 0.342, 0.916; and P= 0.002) as shown in Figure 2F.