EIF2AK3 and familial dilated cardiomyopathy: After the 4-week treatment period, compared with the DCM group, the ZGJTSXF group showed significantly reduced mRNA expression of PERK (Figure 5B), FoxO1 (Figure 5C), Bim (Figure 5D), PUMA (Figure 5E) and TNFSF10 (Figure 5F) in mice with DCM (P < 0.01).