Of which, most genes were involved in malignant tumor progression, such as OBP2B, TNNT1, KLK6, KRT17 etc. Moreover, chemokine signaling pathway and cytokine-cytokine receptor interaction were enriched with the upregulated genes in high-STRA6 groups, indicating STRA6 may engage in the regulation of the immune interaction (Figure 3C). The gene discussed is KRT17; the disease is neoplasm.