Forty-two patients were diagnosed with GH-secreting tumors (32.1%), 21 (16.0%) with prolactinomas, 11 (8.4%) with ACTH-secreting tumors, 6 (4.6%) with gonadotropinomas, 1 (0.8%) with TSH-oma, and 7 (5.3%) with plurihormonal pituitary adenomas. The gene discussed is POMC; the disease is pituitary gland adenoma.