Subsequent tests revealed improved leukocytosis (WBC, 5100 cell/microliter) and anemia (Hb, 12.5 gr/dL); however, the ESR level was still high (87 mm/hour). Due to the iliac abscess and changes in the appendix location, the patient underwent antibiotic therapy for 6 weeks, with suspected appendiceal phlegmon and subsequently, an interval appendectomy was performed after 6 weeks. The pathology report showed involvement of the appendiceal wall by tumoral glands (adenocarcinoma), most probably of gastrointestinal origin. This evidence concerns the gene GSTM1 and anemia (phenotype).