MGMT and neoplasm: Lastly, there is no data provided regarding molecular profiles [e.g., isocitrate dehydrogenase1/2 (IDH1/2)28–30, or O6-methylguanine DNA methyltransferase (MGMT)31–33], the percent of resection or residual tumor volume34–40, Karnofsky Performance Scale (KPS)36,41,42, which may influence our findings on OS.