NOS2 and gastritis: NF-κ B is highly activated at sites of mucosal inflammation where it contributes to the development of gastritis and induces transcription of proinflammatory cytokines, such as tumor necrosis factor-α (TNF-α), IL-1β, IL-6, and IL-8, as well as chemokines, adhesion molecules, matrix metalloproteinases (MMPs), Cox-2, and iNOS [8, 26].