Based on the analysis of the datasets from the GEO database (GES110715) and the online analysis website GEPIA2 (http://gepia2.cancer-pku.cn/#index), we found that the expression of LINC00543 was higher in the CRC tissues as compared with the normal colorectal tissues (Fig. 1a and b). The gene discussed is LINC00543; the disease is colorectal carcinoma.