MEN1 and acute myeloid leukemia: RNA-seq and ChIP-seq analyses in the adult patient-derived cell line MOLM-13 and in pediatric patient-derived AML cells (NCCHD010) with MLL1-r showed that DS-1594a·HCl and DS-1594a·succinate concentration-dependently reduced the expression of MLL-fusion target genes and dissociated the Menin-MLL1 complex from the MEIS1 gene locus.