SMARCE1 and meningioma: While histopathology continued to drive the contemporary grading of meningiomas, interesting corollaries between pathological subtype and molecular findings have been uncovered SMARCE1 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1) mutations were found in almost all cases of meningiomas with clear cell histology (WHO grade 2) and are often mutually exclusively with NF2 loss and non-NF2 mutations [26–29].