CRSwNP patients characterized by eosinophilic inflammation and type 2 inflammation have high levels of immunoglobulin (Ig) E, interleukin (IL‐5), IL‐4 and IL‐13 in local tissues, often accompanied by eosinophilia in peripheral blood.31, 34, 35. The gene discussed is IL5; the disease is chronic rhinosinusitis with nasal polyps.