Not only enzymes such as SOD1, and transcription factors are crucial for cell integrity, but also mechanisms related to copper have been shown to be a prospective therapeutic target for influenza A, lung inflammation, cancer, Alzheimer’s disease, Parkinson’s disease, Menkes disease, and Wilson’s disease, as well as obesity and nonalcoholic fatty liver disease (NAFLD) [37,38]. Here, SOD1 is linked to obesity due to melanocortin 4 receptor deficiency.