MAPT and amyotrophic lateral sclerosis: Other polypeptides implicated in NDDs are tau (linked with AD and FTD) and TAR DNA-binding protein 43 (TDP-43, related to ALS and FTD) [18], but, to the best of our knowledge, epitopes related to these proteins have not yet been produced in plant systems, thus exhibiting a clear area of opportunity for upcoming experiments.