In this section, the different roles of protein kinases in oncogenic transformation and tumor prognosis in the pediatric setting were assessed by two different approaches: by a thorough search of published literature, and by a systematic search in publicly available data retrieved from expression arrays accessed through the R2: Genomics Analysis and Visualization Platform (http://r2.amc.nl (accessed on 15 October 2022)). Here, WEE1 is linked to neoplasm.