TACC1 and dysembryoplastic neuroepithelial tumor: Additionally, FGFR1 fusions (i.e., FGFR1-TACC1), TKD duplications and hotspot mutations (i.e., N5465K and K656E) are frequently observed in certain types of pediatric brain cancer, particularly dysembryoplastic neuroepithelial tumors (DNET) and PA [41].