TBCE and dry eye syndrome: Interestingly, bulk RNA-seq analysis of vehicle (VEH)- or LPS-treated mouse primary KCs [26] revealed that expression levels of genes related to clathrin-dependent or caveolin-mediated endocytosis pathways, but not vesicle fusion process, was elevated along with inflammatory responses and NF-κB signaling pathways in LPS-treated KCs compared to those of VEH-treated KCs (Figure 2c–e).