Vaccination with DCs electroporated with mRNA encoding WT1 (NCT00965224) or WT1, PRAME, and CMVpp65 (NCT01734304) or CT7, MAGE-A3, and WT1 mRNA (NCT01995708) or WT1/PRAME (NCT02405338) mRNA was tested in acute myeloid leukemia (AML). The gene discussed is PRAME; the disease is acute myeloid leukemia.