The MMPs family, including collagenases, stromelysins and stromelysin-like MMPs, matrilysins, gelatinases, MMP19-like MMPs, membrane-type MMPs (MTMMPs), and other MMPs, which is activated by various factors including growth factors, cytokines, physical stress, oncogenic transformation, cell-cell, and cell-ECM interactions, is capable of degrading essential components of the extracellular matrix (ECM), and is involved in tumor invasion and tumor metastasis [39]. Here, MMP7 is linked to neoplasm.