However, the BPBBT concentration in tumor of BPBBT micelles was much lower than that of BPBBT-HSA NPs at 1 h (0.31 versus 3.38% ID/g), 12 h (0.57 versus 7.08% ID/g), 24 h (1.20 versus 9.19% ID/g) and 48 h (1.74 versus 8.23% ID/g) post-injection, respectively. This evidence concerns the gene ALB and neoplasm.