TNFRSF10B and neoplasm: Another combined delivery system for the DR5-targeting antibody (AMG655) was composed of a hydrogel-based chitosan/alginate nanoparticle formulation with encapsulated meso-Tetra(N-methyl-4-pyridyl) porphine tetratosylate (TMP), a hydrophilic photosensitizer that can be used in photodynamic therapy (PDT) to induce cell death through the generation of reactive oxygen species in targeted tumor cells.