TNFSF10 and neoplasm: Subsequently, the BSA NPs were adsorbed by polyethylenimine and then shielded with carboxymethyl chitosan-folate (CMCS-FA) as the outer shell for encapsulating TRAIL protein by the layer-by-layer (LbL) assembly technique, forming the GA/TRAIL co-delivery BSA (GTB) NPs for tumor targeting and synergistic therapy.