CSF-2 contributes to the recruitment of neutrophils and monocytes to the site of infection, the mobilization of monocytes from bone marrow, and stimulates production of CCL2 by neutrophils and macrophages [81,85]; therefore, this cytokine in combination with CCL2 may be involved in phagocytosis at the acute phase of the infection. Here, CCL2 is linked to infection.