IL6 and pulmonary arterial hypertension: Interestingly, the same group recently showed that monocytes overexpressing HERV-K dUTPase release this protein, incorporated into extracellular vesicles (EVs), and cause pulmonary hypertension in association with endothelial mesenchymal transition (EndMT) related to the induction of SNAIL/SLUG, IL-6, and VCAM1 [153].