FA may manifest with mild symptoms, such as abdominal discomfort, nausea, vomiting, or diarrhea, but also with severe, life-threatening symptoms, which may be due to immunoglobulin E (IgE)-mediated hypersensitivity (e.g., anaphylactic shock) (Table 1) or due to severe dehydration and electrolyte imbalance resulting from intense vomiting or diarrhea caused by non-IgE-mediated reactions [2,3]. Here, IGHE is linked to anaphylaxis.