VCAM1 and atherosclerosis: In addition, in terms of anti-inflammatory effects, IRW can increase adenosine triphosphate (ATP) gene expression and reduce the gene expression of inter-cellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion protein 1 (VCAM-1) to reduce leukocyte recruitment in the vascular system, lower the risk of vascular inflammation, and destroy atherosclerosis [17].