In the blue module, Flywch1 (a lncRNA) was linked to three mRNAs (Foxp3, Mef2c, and Serpine1) and enriched in inflammatory bowel disease; transcriptional misregulation in cancer; parathyroid hormone synthesis, secretion, and action; oxytocin signaling pathway; cGMP–PKG signaling pathway; MAPK signaling pathway; Apelin signaling pathway; fluid shear stress and atherosclerosis; AGE–RAGE signaling pathway in diabetic complications; HIF-1 signaling pathway; p53 signaling pathway; and cellular senescence. Here, SERPINE1 is linked to atherosclerosis.