Tacc1 (a lncRNA) was related to 3 mRNAs (Prkce, Ube3a, and Efna5) and abundant in 19 signaling pathway, such as Axon guidance, PI3K–Akt signaling pathway, MAPK signaling pathway, Rap1 signaling pathway, microRNAs in cancer, Ras signaling pathway, insulin resistance, type II diabetes mellitus, and human papillomavirus infection. The gene discussed is EFNA5; the disease is Insulin resistance.