CXCL8 and colon adenocarcinoma: Abbasi et al. compared the cellular inflammation inhibitory effects of polyphenols obtained from agro-industrial by-products and observed that the expression of inflammatory factor interleukin-8 (IL-8) in human colon adenocarcinoma (Caco-2) cells was greatly reduced with grape pomace and spent coffee ground polyphenol extracts treatment [11].